For over 30 years, the KEMRI-Wellcome Trust programme has been interested in how malaria parasite exposure affects disease outcomes in African children. In 1996, with the formation of a Pan-African collaboration to develop a cartography of malaria parasite exposure across Africa – The Mapping Malaria Risk in Africa (MARA) project. 

In 2005, Professor Bob Snow established the Malaria Atlas Project in Kenya, to continue the work initiated by MARA in Africa and beyond to provide a global risk analysis of malaria infection. In 2013, the INFORM (Information for Malaria) project was established by Professors Abdisalan Mohamed Noor and Bob Snow in Kenya to support regional national malaria control programmes develop national risk maps to tailor sub-national control. Since 2013, epidemiological profiles were developed in partnership with ministries of health in Kenya, Tanzania, Uganda, Somalia, Sudan, South Sudan, Nigeria, Malawi, Mali, Ghana, Ethiopia, Democratic Republic of Congo, Madagascar, Rwanda, Eritrea, Djibouti, Mozambique, Benin, Cote D’Ivoire and Yemen.